Santiago's five-star hotels deliver more than a place to sleep - they offer rooftop pools with Andes views, historic mansions turned boutique stays, and business districts minutes from fine dining. Whether you're in town for work or leisure, these properties put you close to key landmarks like Cerro Santa Lucía, Parque Arauco, and the airport.
Rates at five-star properties range from roughly $150 to $400 per night, depending on season and district. The upscale El Golf neighborhood hosts corporate favorites like the W Santiago and Santiago Marriott, while Lastarria's cultural charm shines at Hotel Magnolia. For a smart choice near the airport, Wyndham Santiago Aeropuerto includes a free shuttle - ideal for layovers. Most hotels feature free WiFi, fitness centers, pools, and on-site dining; some add spas, free parking, or airport shuttles. Book now to secure the best rates across these 16 options.